In conclusion, we can say that the choice between Dermicool Prickly Heat Powder and Medicated Powders strictly depends on your preferences and needs. If you are looking for Quick relief that cools your body, fights bacteria and absorbs sweat, then go for Dermicool Prickly Heat Powder. However, if you're having inflammation and are looking for a powder to reduce it and dry up the moisture that causes prickly heat, go for Medicated Powders like Calamine. But it's essential to note that Calamine doesn't have cooling properties and won't help in relieving the heat and itch caused by Prickly Heat.